Process for manufacturing of propantriol from sugar



UNITED- STATES PATENT, OFFICE.

WILHELM cormsrnm, or BERLIN, AND KARL LiiDEcKE, or WILMERSDORF, NEAR BERLIN, GERMANY.

PROCESS FOR'MANUIEAC'IURING OF PROPAN'IRIOL FROM SUGAR.

No Drawing T all whom it may concern:

Be it known that we, WILrrsLM CONN- STEIN, chemist, a citizen of Prussia, and residin at Fasanenstreet 27, Berlin, Germany, and 1%.5121. Liinncxn, a citizen of Prussia and residing at Kaiser Allee 156, Wilmersdorf, near Berlin, Germany, have invented a new and useful Improvement in Processes for Manufacturing of Propantriol from Sugar; and we do hereby declare the following to be a full, clear, and exact descriptionof the same.

In a copending application Serial Niunber 317,324 filed Aug. 13, 1919, a process for manufacturing propantriol from sugar by fermentation in the presence of alkaline reacting salts has been described. The present process for manufacturing propantriol consists in adding nonallialine reacting salts 2'. 6. neutral or acid reacting salts to sugar and causing the mixture to be fermented above the formation of 3% propantriol from the used sugar and until the disappearance of the sugar. As sugar we may use all sorts of fermentable sugars: saccharose, dextrose, levulose, invert sugar, maltose, molasses, etc.

. As salts we may useall soluble salts having no poisonous action on yeast.

Example I. 1000 grams sugars, 900 grams crystallised ferrous-sulfate and the following nutritive salts: 8 grams ammonium sulfate, grams sodium phosphate, 2 grams potassium sulfate, 7 grams magnesium sulfate are dissolved in 10 liters water and 100 grams yeast (commercial press yeast or cultivated pure races) are added. One allows the mixture to stand at about 3085 centigrade. After 5 days the sugar hasdisappeared, which may be determined by the known reactions.

7 About 125 grams propantriol, i. 6. 12.5%

from the sugar, has been-formed.

For isolating the propantriol one may evaporate the mixture to a degree that the ferrous sulfate may'crystallize. The uncrystallized portion of ferrous sulfate is precipitated with lime, one filtrates, acidulates the filtrate with a" small-surplus of-sulfuric acid and evaporates until the formation of a light brown syrup which contains after filtration about 80%: propantriol. One may also extract the propantriol from the evaporated syrup by means: of alcohol-and may decolor- Specification of Letters Patent.

Application filed August 13, 1919. Serial No.

Patented Feb. 8, 1921. 317,325.

Example II.

1500 grams sugar, 1200 grams crystallized aluminium sulfate and as nutritive salts: grams ammonium sulfate, 8 grams sodium phosphate, 4: grams potassium sulfate, 10 grams magnesium sulfate are dissolved in liters water and mixed with 150 grams yeast.

The further treatment may be carried out aocording to Example 1. One obtains about 200 grams propantriol.

Ezuample III.

1000 grams sugar, 300 grams ammonium chlorid and as nutritive salts: 10 grams ammonium sulfate, 7 grams sodium phosphate,

nesium sulfate are dissolved in 9 liters water 3 grams potassium sulfate and 8 grams magand added with 100 grams yeast. 'After 4:. L

days having stood at 3035" centigrade the sugar has disappeared. The liquid contains about 75 grams propantriol. The further treatment may be carried out as in Example l.

Example IV.

; 1000 grams sugar, 400 grams calcium-chlorid free of water and as nutritive salts: 8,

- grams ammonium sulfate, 5 grams sodium phosphate, 2 gramspotassium sulfate are dissolved in 10 liters water. One addslOO' grams yeast and'all ows to stand at 30735? centigrade. After 6 days the sugar has disappeared and the solution contains about 85 grams propantriolf One adds to the hot liquid sodium carbonate until further additions do not cause a precipitate. Then one filters from the precipitated calcium carbonate, acidulates the filtrate'with hydrochloric acid until a slight acid reaction and evaporates the liquid to syrupy consistency. The obtained is extractedfwithabsolute alcohol, the 'alcoholic liquid treated with decolorizingcarbon magma contammg sodium chlorid,

and the alcohol is evaporated. The remaining light brown syrup contains 80-85% propantriol,- which may be recovered by disti1- wlation with superheated steam under diminished pressure. We claim: A process of obtaining propantriol, comprising mixing sugar-contaimng solutions with water-soluble salts of non-alkaline reaction in lar er amounts than sufiicient to form nutrients or yeast, adding yeast, and then names to this specification in the presence of 15 two subscribing witnesses.

WILHELM coNNsTErN. DR. KARL LUDEOKE. Witnesses J ULIUS FRANKIE,

ERNA WOLFE. 

